Handbook of Advanced Chromatography / Mass Spectrometry Techniques
Chapter 10 - MultipleParallel Mass Spectrometry for Liquid Chromatography
by
 William Craig Byrdwell

Figure 10-4. Arrangement of instruments for the first report of LC1/MS4, quadruple parallel mass spectrometry. Effluent after the UV detector (nondestructive) is split via Valco tees and fused-silica capillary tubing to go to various mass spectrometers and other detectors (ELSD and CAD). Electrolyte is supplied via syringe pump for electrospray ionization mass spectrometry and acetone dopant supplied via by an Agilent 1290 for APPI-MS. High- and lowsensitivity atmospheric pressure chemical ionization mass spectrometry used for vitamin D and triacylglycerols, respectively. APPI, atmospheric pressure photoionization; CAD, charged aerosol detector; ELSD, evaporative light scattering detector.

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