Handbook of Advanced Chromatography / Mass Spectrometry Techniques
Chapter 7 - Introduction to Two-Dimensional Liquid Chromatography - Theory and Practice
by Dwight R. Stoll

Figure 7-15. Time required to reach 50% probability of resolving all of the components in a mixture for different liquid chromatography (LC) techniques: one-dimensional liquid chromatography [ (light gray in print versions)], LC x LC (B), sLC x LC [ (dark gray in print versions)]. The red (gray in print versions) line is an interpolation between the times for 10 and 12 sample components. sLC x LC, selective comprehensive two-dimensional liquid chromatography.

Adapted from Davis, J.M., Stoll, D.R., 2014. Likelihood of total resolution in liquid chromatography: evaluation of onedimensional, comprehensive two-dimensional, and selective comprehensive two-dimensional liquid chromatography. J. Chromatogr. A 1360, 128-142. http://dx.doi.org/10.1016/j.chroma.2014.07.066

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