Scheme of the preparation of a capillary column using the “slurry” packing procedure. I: packing of the SP; II: flushing with water; III: inlet frit preparation with a heated wire; IV: outlet frit preparation; VI: removal of excess SP; VII: removal of the polyimide external layer for the detection window.
Reproduced from Fanali, C., Asensio-Ramos, M., Hernández-Borges, J., Rocco, A., Fanali, S., 2011. Nano-liquid chromatographic separations. In: Byrdwell, W.C., Holčapek, M. (Eds.), Extreme Chromatography: Faster, Hotter, Smaller. American Oil Chemists’ Society (AOCS), Urbana, IL, USA, pp. 301-380.
Scheme of capillary liquid chromatography coupled with nuclear magnetic resonance (NMR) through a continuous flow NMR probe. HPLC, high-performance liquid chromatography.
Schematic representation of a column-switching system coupled with mass spectrometry (MS). ESI, electrospray ionization.
Scheme of a multidimensional approach utilizing a global N-glycome characterization followed by parallel analysis of deglycosylated and glycosylated peptides with orthogonal fractionation.
Reprinted from Parker, B.L., Thaysen-Andersen, M., Solis, N., Scott, N.E., Larsen, M.R., Graham, M.E., Packer, N.H., Cordwell, S.J., 2013. Site-specific glycan-peptide analysis for determination of N glycoproteome heterogeneity. J. Proteome Res. 12, 5791-5800 with permission from ACS Publications.
Schematic illustration of two versions of the original high performance liquid chromatography chip.
Reprinted from Zhao, C., Wu, Z., Xue, G., Wang, J., Zhao, Y., Xu, Z., Lin, D., Herbert, G., Chang, Y., Cai, K., Xu, G., 2011. Ultra-high capacity liquid chromatography chip/quadrupole time-of-flight mass spectrometry for pharmaceutical analysis. J. Chromatogr. A 1218, 3669-3674 with permission from Elsevier.
Nano-liquid chromatography-electrospray ionization mass spectrometry base peak chromatogram of the anthocyanin content of a commercial blueberry juice.
Reprinted from Fanali, C., Dugo, L., D’Orazio, G., Lirangi, M., Dachá, M., Dugo, P., Mondello, L., 2011b. Analysis of anthocyanins in commercial fruit juices by using nano-liquid chromatography-electrospray-mass spectrometry and high-performance liquid chromatography with UV-vis detector. J. Sep. Sci. 34, 150-159 with permission from Wiley-VCH.
The Handbook of Advanced Chromatography /Mass Spectrometry Techniques is a compendium of new and advanced analytical techniques that have been developed in recent years for analysis of all types of molecules in a variety of complex matrices, from foods to fuel to pharmaceuticals and more. Focusing on areas that are becoming widely used or growing rapidly, this is a comprehensive volume that describes both theoretical and practical aspects of advanced methods for analysis. Written by authors who have published the foundational works in the field, the chapters have an emphasis on lipids, but reach a broader audience by including advanced analytical techniques applied to a variety of fields.
Contains both practical and theoretical knowledge, providing core understanding for implementing modern chromatographic and mass spectrometric techniques Presents chapters on the most popular and fastest-growing new techniques being implemented in diverse areas of research.
The Handbook is intended for upper level undergraduate students and graduate students, researchers, technicians, and scientists.It is also well suited for advanced analytical instrumentation students as well as for analysts seeking additional knowledge or a deeper understanding of familiar techniques.
No. of pages: 520
Copyright: © Academic Press and AOCS Press 2017
Published: September 11th 2017
eBook ISBN: 9780128117330
Paperback ISBN: 9780128117323